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#QuestionSubject and topicDifficulty
101 Which bond links adjacent nucleotides in a DNA strand? Biology/Biological Studies/Biotechnology/Biochemistry
DNA structure and packaging
Easy
102 A nucleosome core consists of DNA wrapped around Biology/Biological Studies/Biotechnology/Biochemistry
DNA structure and packaging
Easy
103 A double-stranded DNA sample has 20% adenine. What is the percentage of guanine? Biology/Biological Studies/Biotechnology/Biochemistry
DNA structure and packaging
Medium
104 Why are histone proteins positively charged? Biology/Biological Studies/Biotechnology/Biochemistry
DNA structure and packaging
Medium
105 If the distance between two consecutive base pairs is 0.34 nm, what is the approximate total length of DNA in… Biology/Biological Studies/Biotechnology/Biochemistry
DNA structure and packaging
Hard
106 Which enzyme joins the discontinuously synthesised fragments of the lagging strand? Biology/Biological Studies/Biotechnology/Biochemistry
DNA replication
Easy
107 Meselson and Stahl separated DNA of different densities using Biology/Biological Studies/Biotechnology/Biochemistry
DNA replication
Easy
108 In the Meselson–Stahl experiment, what was observed after one generation in ¹⁴N medium? Biology/Biological Studies/Biotechnology/Biochemistry
DNA replication
Medium
109 Why is DNA synthesis continuous on one strand but discontinuous on the other? Biology/Biological Studies/Biotechnology/Biochemistry
DNA replication
Medium
110 E. coli cells with fully ¹⁵N-labelled DNA are grown in ¹⁴N medium for three generations. What fraction of DNA… Biology/Biological Studies/Biotechnology/Biochemistry
DNA replication
Hard
111 In eukaryotes, which RNA polymerase transcribes the precursor of mRNA (hnRNA)? Biology/Biological Studies/Biotechnology/Biochemistry
Transcription
Easy
112 The removal of introns and joining of exons in hnRNA is called Biology/Biological Studies/Biotechnology/Biochemistry
Transcription
Easy
113 The coding strand of a gene reads 5′-ATGCCA-3′. What will be the sequence of the RNA transcribed from it? Biology/Biological Studies/Biotechnology/Biochemistry
Transcription
Medium
114 In bacteria, which factor helps RNA polymerase to terminate transcription? Biology/Biological Studies/Biotechnology/Biochemistry
Transcription
Medium
115 Why can translation begin before transcription is complete in bacteria but not in eukaryotes? Biology/Biological Studies/Biotechnology/Biochemistry
Transcription
Hard
116 Which codon acts as the start codon and also codes for methionine? Biology/Biological Studies/Biotechnology/Biochemistry
Genetic code and translation
Easy
117 The fact that some amino acids are coded by more than one codon shows that the genetic code is Biology/Biological Studies/Biotechnology/Biochemistry
Genetic code and translation
Easy
118 Which part of a tRNA recognises the codon on mRNA? Biology/Biological Studies/Biotechnology/Biochemistry
Genetic code and translation
Medium
119 The coding region of an mRNA, from the start codon AUG to the stop codon (both included), has 300 nucleotides… Biology/Biological Studies/Biotechnology/Biochemistry
Genetic code and translation
Medium
120 In bacteria, which molecule catalyses peptide bond formation during translation? Biology/Biological Studies/Biotechnology/Biochemistry
Genetic code and translation
Hard
121 In the lac operon, which gene codes for β-galactosidase? Biology/Biological Studies/Biotechnology/Biochemistry
Regulation of gene expression
Easy
122 What is the role of lactose in the lac operon? Biology/Biological Studies/Biotechnology/Biochemistry
Regulation of gene expression
Easy
123 In the absence of lactose, the lac operon is switched off because Biology/Biological Studies/Biotechnology/Biochemistry
Regulation of gene expression
Medium
124 Regulation of the lac operon by the repressor is an example of Biology/Biological Studies/Biotechnology/Biochemistry
Regulation of gene expression
Medium
125 A mutant E. coli has a repressor that cannot bind lactose but can still bind the operator. What will happen w… Biology/Biological Studies/Biotechnology/Biochemistry
Regulation of gene expression
Hard
126 In which year was the Human Genome Project completed? Biology/Biological Studies/Biotechnology/Biochemistry
Human Genome Project and DNA fingerprinting
Easy
127 Which human chromosome was found to have the fewest genes? Biology/Biological Studies/Biotechnology/Biochemistry
Human Genome Project and DNA fingerprinting
Easy
128 The probe used by Alec Jeffreys for DNA fingerprinting was based on Biology/Biological Studies/Biotechnology/Biochemistry
Human Genome Project and DNA fingerprinting
Medium
129 What is the correct order of steps in DNA fingerprinting? Biology/Biological Studies/Biotechnology/Biochemistry
Human Genome Project and DNA fingerprinting
Medium
130 Why can DNA fingerprinting distinguish between two individuals even though 99.9% of their bases are identical? Biology/Biological Studies/Biotechnology/Biochemistry
Human Genome Project and DNA fingerprinting
Hard
131 Which scientist disproved spontaneous generation using pre-sterilised flasks? Biology/Biological Studies/Biotechnology/Biochemistry
Origin of life
Easy
132 Which gases did Miller use in his experiment along with water vapour? Biology/Biological Studies/Biotechnology/Biochemistry
Origin of life
Easy
133 What was the main product detected in Miller's original experiment? Biology/Biological Studies/Biotechnology/Biochemistry
Origin of life
Medium
134 Oparin and Haldane proposed that the first life was preceded by Biology/Biological Studies/Biotechnology/Biochemistry
Origin of life
Medium
135 Why was the early Earth's atmosphere important for Miller's results? Biology/Biological Studies/Biotechnology/Biochemistry
Origin of life
Hard
136 The forelimbs of a whale, a bat and a human are examples of Biology/Biological Studies/Biotechnology/Biochemistry
Evidence for evolution
Easy
137 The wings of a butterfly and of a bird are Biology/Biological Studies/Biotechnology/Biochemistry
Evidence for evolution
Easy
138 The thorn of Bougainvillea and the tendril of Cucurbita illustrate Biology/Biological Studies/Biotechnology/Biochemistry
Evidence for evolution
Medium
139 In industrial areas of England, dark moths became more common after 1850 mainly because Biology/Biological Studies/Biotechnology/Biochemistry
Evidence for evolution
Medium
140 Which pair shows convergent evolution? Biology/Biological Studies/Biotechnology/Biochemistry
Evidence for evolution
Hard
141 According to Darwin, the fitness of an individual ultimately refers to its Biology/Biological Studies/Biotechnology/Biochemistry
Darwin and natural selection
Easy
142 Darwin's finches of the Galapagos Islands are an example of Biology/Biological Studies/Biotechnology/Biochemistry
Darwin and natural selection
Easy
143 Which naturalist independently reached conclusions similar to Darwin's while working in the Malay Archipelago? Biology/Biological Studies/Biotechnology/Biochemistry
Darwin and natural selection
Medium
144 Lamarck suggested that the giraffe's long neck arose because ancestors stretched to reach leaves and passed o… Biology/Biological Studies/Biotechnology/Biochemistry
Darwin and natural selection
Medium
145 The Tasmanian wolf (a marsupial) and the placental wolf look similar. This similarity is best explained by Biology/Biological Studies/Biotechnology/Biochemistry
Darwin and natural selection
Hard
146 Hugo de Vries based his mutation theory on studies of Biology/Biological Studies/Biotechnology/Biochemistry
Mechanisms of evolution
Easy
147 A random change in allele frequency in a small population is called Biology/Biological Studies/Biotechnology/Biochemistry
Mechanisms of evolution
Easy
148 A small group of birds is blown to an island and starts a new population whose allele frequencies differ from… Biology/Biological Studies/Biotechnology/Biochemistry
Mechanisms of evolution
Medium
149 In a bird population, both very small and very large beaks become common while medium beaks become rare. This… Biology/Biological Studies/Biotechnology/Biochemistry
Mechanisms of evolution
Medium
150 How do de Vries's mutations differ from the variations Darwin described? Biology/Biological Studies/Biotechnology/Biochemistry
Mechanisms of evolution
Hard